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Anti-TNF Therapy Reduces Serum Levels of Chemerin in Rheumatoid Arthritis: A New Mechanism by Which Anti-TNF Might Reduce Inflammation

BACKGROUND: Chemerin is a specific chemoattractant for macrophages and dendritic cells (DC). In addition, it can rapidly stimulate macrophage adhesion to extracellular matrix proteins and adhesion molecules and is able to activate fibroblast-like synoviocytes (FLS), suggesting a role in the pathogen...

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Detalles Bibliográficos
Autores principales: Herenius, Marieke M. J., Oliveira, Ana S. F., Wijbrandts, Carla A., Gerlag, Daniëlle M., Tak, Paul P., Lebre, Maria C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584053/
https://www.ncbi.nlm.nih.gov/pubmed/23460910
http://dx.doi.org/10.1371/journal.pone.0057802