Vitamin D Status, Filaggrin Genotype, and Cardiovascular Risk Factors: A Mendelian Randomization Approach

BACKGROUND: Vitamin D deficiency is associated with increased cardiovascular disease risk in observational studies. Whether these associations are causal is not clear. Loss-of-function mutations in the filaggrin gene result in up to 10% higher serum vitamin D concentrations, supposedly due to a decr...

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Detalles Bibliográficos
Autores principales: Skaaby, Tea, Husemoen, Lise Lotte Nystrup, Martinussen, Torben, Thyssen, Jacob P., Melgaard, Michael, Thuesen, Betina Heinsbæk, Pisinger, Charlotta, Jørgensen, Torben, Johansen, Jeanne D., Menné, Torkil, Carlsen, Berit, Szecsi, Pal B., Stender, Steen, Fenger, Runa Vavia, Fenger, Mogens, Linneberg, Allan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584055/
https://www.ncbi.nlm.nih.gov/pubmed/23460889
http://dx.doi.org/10.1371/journal.pone.0057647

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584055/
https://www.ncbi.nlm.nih.gov/pubmed/23460889
http://dx.doi.org/10.1371/journal.pone.0057647

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