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Warburg and Crabtree Effects in Premalignant Barrett's Esophagus Cell Lines with Active Mitochondria

BACKGROUND: Increased glycolysis is a hallmark of cancer metabolism, yet relatively little is known about this phenotype at premalignant stages of progression. Periodic ischemia occurs in the premalignant condition Barrett's esophagus (BE) due to tissue damage from chronic acid-bile reflux and...

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Detalles Bibliográficos
Autores principales: Suchorolski, Martin T., Paulson, Thomas G., Sanchez, Carissa A., Hockenbery, David, Reid, Brian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584058/
https://www.ncbi.nlm.nih.gov/pubmed/23460817
http://dx.doi.org/10.1371/journal.pone.0056884