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Minor Groove Binder Distamycin Remodels Chromatin but Inhibits Transcription
The condensed structure of chromatin limits access of cellular machinery towards template DNA. This in turn represses essential processes like transcription, replication, repair and recombination. The repression is alleviated by a variety of energy dependent processes, collectively known as “chromat...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584068/ https://www.ncbi.nlm.nih.gov/pubmed/23460895 http://dx.doi.org/10.1371/journal.pone.0057693 |