An ACACB Variant Implicated in Diabetic Nephropathy Associates with Body Mass Index and Gene Expression in Obese Subjects

Acetyl coenzyme A carboxylase B gene (ACACB) single nucleotide polymorphism (SNP) rs2268388 is reproducibly associated with type 2 diabetes (T2DM)-associated nephropathy (DN). ACACB knock-out mice are also protected from obesity. This study assessed relationships between rs2268388, body mass index (...

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Detalles Bibliográficos
Autores principales: Ma, Lijun, Murea, Mariana, Snipes, James A., Marinelarena, Alejandra, Krüger, Jacqueline, Hicks, Pamela J., Langberg, Kurt A., Bostrom, Meredith A., Cooke, Jessica N., Suzuki, Daisuke, Babazono, Tetsuya, Uzu, Takashi, Tang, Sydney C. W., Mondal, Ashis K., Sharma, Neeraj K., Kobes, Sayuko, Antinozzi, Peter A., Davis, Matthew, Das, Swapan K., Rasouli, Neda, Kern, Philip A., Shores, Nathan J., Rudel, Lawrence L., Blüher, Matthias, Stumvoll, Michael, Bowden, Donald W., Maeda, Shiro, Parks, John S., Kovacs, Peter, Hanson, Robert L., Baier, Leslie J., Elbein, Steven C., Freedman, Barry I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584087/
https://www.ncbi.nlm.nih.gov/pubmed/23460794
http://dx.doi.org/10.1371/journal.pone.0056193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584087/
https://www.ncbi.nlm.nih.gov/pubmed/23460794
http://dx.doi.org/10.1371/journal.pone.0056193

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