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Digital PCR to Detect and Quantify Heteroresistance in Drug Resistant Mycobacterium tuberculosis

Drug resistance in Mycobacterium tuberculosis presents an enormous public health threat. It is typically defined as >1% of drug resistant colonies using the agar proportion method. Detecting small numbers of drug resistant Tb in a population, also known as heteroresistance, is challenging with cu...

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Detalles Bibliográficos
Autores principales: Pholwat, Suporn, Stroup, Suzanne, Foongladda, Suporn, Houpt, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584134/
https://www.ncbi.nlm.nih.gov/pubmed/23468945
http://dx.doi.org/10.1371/journal.pone.0057238