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Digital PCR to Detect and Quantify Heteroresistance in Drug Resistant Mycobacterium tuberculosis
Drug resistance in Mycobacterium tuberculosis presents an enormous public health threat. It is typically defined as >1% of drug resistant colonies using the agar proportion method. Detecting small numbers of drug resistant Tb in a population, also known as heteroresistance, is challenging with cu...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584134/ https://www.ncbi.nlm.nih.gov/pubmed/23468945 http://dx.doi.org/10.1371/journal.pone.0057238 |