Improvement in Prediction of Coronary Heart Disease Risk over Conventional Risk Factors Using SNPs Identified in Genome-Wide Association Studies

OBJECTIVE: We examined whether a panel of SNPs, systematically selected from genome-wide association studies (GWAS), could improve risk prediction of coronary heart disease (CHD), over-and-above conventional risk factors. These SNPs have already demonstrated reproducible associations with CHD; here...

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Detalles Bibliográficos
Autores principales: Bolton, Jennifer L., Stewart, Marlene C. W., Wilson, James F., Anderson, Niall, Price, Jackie F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584137/
https://www.ncbi.nlm.nih.gov/pubmed/23468967
http://dx.doi.org/10.1371/journal.pone.0057310

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584137/
https://www.ncbi.nlm.nih.gov/pubmed/23468967
http://dx.doi.org/10.1371/journal.pone.0057310

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