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Improvement in Prediction of Coronary Heart Disease Risk over Conventional Risk Factors Using SNPs Identified in Genome-Wide Association Studies
OBJECTIVE: We examined whether a panel of SNPs, systematically selected from genome-wide association studies (GWAS), could improve risk prediction of coronary heart disease (CHD), over-and-above conventional risk factors. These SNPs have already demonstrated reproducible associations with CHD; here...
Autores principales: | Bolton, Jennifer L., Stewart, Marlene C. W., Wilson, James F., Anderson, Niall, Price, Jackie F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584137/ https://www.ncbi.nlm.nih.gov/pubmed/23468967 http://dx.doi.org/10.1371/journal.pone.0057310 |
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