Robust, synergistic regulation of human gene expression using TALE activators

Artificial transcription activator-like (TAL) effector-based activators (TALE activators) have broad utility but previous studies suggest that these monomeric proteins often possess low activities. Here we demonstrate that TALE activators can robustly function individually or in synergistic combinat...

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Detalles Bibliográficos
Autores principales: Maeder, Morgan L., Linder, Samantha J., Reyon, Deepak, Angstman, James F., Fu, Yanfang, Sander, Jeffry D., Joung, J. Keith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584229/
https://www.ncbi.nlm.nih.gov/pubmed/23396285
http://dx.doi.org/10.1038/nmeth.2366

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584229/
https://www.ncbi.nlm.nih.gov/pubmed/23396285
http://dx.doi.org/10.1038/nmeth.2366

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