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Robust, synergistic regulation of human gene expression using TALE activators
Artificial transcription activator-like (TAL) effector-based activators (TALE activators) have broad utility but previous studies suggest that these monomeric proteins often possess low activities. Here we demonstrate that TALE activators can robustly function individually or in synergistic combinat...
Autores principales: | Maeder, Morgan L., Linder, Samantha J., Reyon, Deepak, Angstman, James F., Fu, Yanfang, Sander, Jeffry D., Joung, J. Keith |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584229/ https://www.ncbi.nlm.nih.gov/pubmed/23396285 http://dx.doi.org/10.1038/nmeth.2366 |
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