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The helminth product, ES-62, protects against airway inflammation by resetting the Th cell phenotype

We previously demonstrated inhibition of ovalbumin-induced allergic airway hyper-responsiveness in the mouse using ES-62, a phosphorylcholine-containing glycoprotein secreted by the filarial nematode, Acanthocheilonema viteae. This inhibition correlated with ES-62-induced mast cell desensitisation,...

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Detalles Bibliográficos
Autores principales: Rzepecka, Justyna, Siebeke, Ivonne, Coltherd, Jennifer C., Kean, Dorothy E., Steiger, Christina N., Al-Riyami, Lamyaa, McSharry, Charles, Harnett, Margaret M., Harnett, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584281/
https://www.ncbi.nlm.nih.gov/pubmed/23291461
http://dx.doi.org/10.1016/j.ijpara.2012.12.001