Lysosomal Trafficking, Antigen Presentation, and Microbial Killing Are Controlled by the Arf-like GTPase Arl8b

Antigen presentation and microbial killing are critical arms of host defense that depend upon cargo trafficking into lysosomes. Yet, the molecular regulators of traffic into lysosomes are only partly understood. Here, using a lysosome-dependent immunological screen of a trafficking shRNA library, we...

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Detalles Bibliográficos
Autores principales: Garg, Salil, Sharma, Mahak, Ung, Cindy, Tuli, Amit, Barral, Duarte C., Hava, David L., Veerapen, Natacha, Besra, Gurdyal S., Hacohen, Nir, Brenner, Michael B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584282/
https://www.ncbi.nlm.nih.gov/pubmed/21802320
http://dx.doi.org/10.1016/j.immuni.2011.06.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584282/
https://www.ncbi.nlm.nih.gov/pubmed/21802320
http://dx.doi.org/10.1016/j.immuni.2011.06.009

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