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Regulation of the Cardiac Sodium/Bicarbonate Cotransporter by Angiotensin II: Potential Contribution to Structural, Ionic and Electrophysiological Myocardial Remodelling

The sodium/ bicarbonate cotransporter (NBC) is, with the Na(+)/H(+) exchanger (NHE), an important alkalinizing mechanism that maintains cellular intracellular pH (pHi). In the heart exists at least three isoforms of NBC, one that promotes the co-influx of 1 molecule of Na(+) per 1molecule of HCO(3)(...

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Detalles Bibliográficos
Autores principales: Aiello, Ernesto Alejandro, Giusti, Verónica Celeste De
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584305/
https://www.ncbi.nlm.nih.gov/pubmed/23116057
http://dx.doi.org/10.2174/157340313805076340