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Use of Integrase-Minus Lentiviral Vector for Transient Expression

OBJECTIVE: Lentivirus-derived vectors are among the most promising viral vectors for gene therapy which is currently available, but their use in clinical practice is limited due to associated risk of insertional mutagenesis. Gene targeting is an ideal method for gene therapy, but it has low efficien...

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Detalles Bibliográficos
Autores principales: Farazmandfar, Touraj, Khanahmad Shahreza, Hossein, Haghshenas, Mohammad Reza, Janbabai, Ghasem, Azadeh, Hossein, Mansour Samaei, Nader
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royan Institute 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584425/
https://www.ncbi.nlm.nih.gov/pubmed/23508124