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Zoledrinic Acid Induces Steoblastic Differentiation of Mesenchymal Stem Cells without Change in Hypomethylation Status of OSTERIX Promoter

OBJECTIVE: Mechanism of zoledronic acid on osteoblastic differentiation of mesenchymal stem cells (MSCs) has not fully understood. With the knowledge of some drugs mechanism that alter methylation pattern of some genes, the present research sets out to evaluate osterix (OSX) promoter methylation pat...

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Detalles Bibliográficos
Autores principales: Farshdousti Hagh, Majid, Noruzinia, Mehrdad, Mortazavi, Yousef, Soleimani, Masoud, Kaviani, Saeid, Mahmodinia Maymand, Maryam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royan Institute 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584426/
https://www.ncbi.nlm.nih.gov/pubmed/23508196