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BRCA1 Protein Expression Level and CD44(+)Phenotype in Breast Cancer Patients

OBJECTIVE: CD44(+)/CD24(-/low) breast cancer cells have tumour-initiating properties with stem cell-like features. Breast cancer gene 1 (BRCA1) is a tumour suppressor gene that plays a crucial role in DNA repair and maintenance of chromosome stability. The clinicopatho- logical features of breast ca...

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Detalles Bibliográficos
Autores principales: Madjd, Zahra, Karimi, Adel, Molanae, Saadat, Asadi-Lari, Mohsen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royan Institute 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584470/
https://www.ncbi.nlm.nih.gov/pubmed/23508738