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Blockade of irradiation-induced autophagosome formation impairs proliferation but does not enhance cell death in HCT-116 human colorectal carcinoma cells

This work was undertaken to gain further information on the molecular mechanisms underlying autophagosome formation and its relation with tumor cell survival in response to radiation in colon cancer. A human colon cancer cell line, HCT-116, was examined with respect to cell survival after blockade o...

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Detalles Bibliográficos
Autores principales: DE ALBUQUERQUE-XAVIER, ANA CRISTINA, BASTOS, LILIAN GONÇALVES R., DE FREITAS, JULIO CESAR MADUREIRA, LEVE, FERNANDA, DE SOUZA, WALDEMIR FERNÁNDEZ, DE ARAUJO, WALLACE MARTINS, WANDERLEY, JOÃO LUIZ MENDES, TANAKA, MARCELO NEVES, DE SOUZA, WANDERLEY, MORGADO-DÍAZ, JOSÉ ANDRÉS
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584567/
https://www.ncbi.nlm.nih.gov/pubmed/22246348
http://dx.doi.org/10.3892/ijo.2012.1329