RNAi-mediated knockdown of ERK1/2 inhibits cell proliferation and invasion and increases chemosensitivity to cisplatin in human osteosarcoma U2-OS cells in vitro

Osteosarcoma is the most common primary malignancy of the bone. There have been some advances in surgical and chemotherapeutic strategies, but it is still a tumor with a high mortality rate in children and young adults. Mitogen-activated protein kinase/extracellular signal regulated kinase (ERK) pat...

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Detalles Bibliográficos
Autores principales: SI, HAIPENG, PENG, CHANGLIANG, LI, JINGJING, WANG, XIQIAN, ZHAI, LIANWEN, LI, XIAOFENG, LI, JIANMIN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2011
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584577/
https://www.ncbi.nlm.nih.gov/pubmed/22179790
http://dx.doi.org/10.3892/ijo.2011.1303

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584577/
https://www.ncbi.nlm.nih.gov/pubmed/22179790
http://dx.doi.org/10.3892/ijo.2011.1303

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