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Augmentation of autologous bone graft by a combination of bone morphogenic protein and bisphosphonate increased both callus volume and strength

BACKGROUND AND PURPOSE: Bone morphogenic proteins (BMPs) can be used in non-unions to replace autograft. BMPs induce osteoblasts and (less well known) also osteoclasts, which can in turn be controlled by a bisphosphonate. In the present study, our aim was to improve the biological effect of autologo...

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Detalles Bibliográficos
Autores principales: Bosemark, Per, Isaksson, Hanna, McDonald, Michelle M, Little, David G, Tägil, Magnus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Informa Healthcare 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584593/
https://www.ncbi.nlm.nih.gov/pubmed/23409846
http://dx.doi.org/10.3109/17453674.2013.773123