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Augmentation of autologous bone graft by a combination of bone morphogenic protein and bisphosphonate increased both callus volume and strength
BACKGROUND AND PURPOSE: Bone morphogenic proteins (BMPs) can be used in non-unions to replace autograft. BMPs induce osteoblasts and (less well known) also osteoclasts, which can in turn be controlled by a bisphosphonate. In the present study, our aim was to improve the biological effect of autologo...
Autores principales: | Bosemark, Per, Isaksson, Hanna, McDonald, Michelle M, Little, David G, Tägil, Magnus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Informa Healthcare
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584593/ https://www.ncbi.nlm.nih.gov/pubmed/23409846 http://dx.doi.org/10.3109/17453674.2013.773123 |
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