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In vitro expansion of human glioblastoma cells at non-physiological oxygen tension irreversibly alters subsequent in vivo aggressiveness and AC133 expression

Among markers of glioblastoma initiating cells, AC133 has been shown to be associated with glioblastoma resistance and malignancy. Recently, it was demonstrated that increasing oxygen tension (pO(2)) down-regulated AC133 expression in glioblastoma cells in vitro. In order to better understand extrin...

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Detalles Bibliográficos
Autores principales: BOURSEAU-GUILMAIN, ERIKA, LEMAIRE, LAURENT, GRIVEAU, AUDREY, HERVOUET, ERIC, VALLETTE, FRANÇOIS, BERGER, FRANÇOIS, MENEI, PHILIPPE, BENOIT, JEAN-PIERRE, WION, DIDIER, GARCION, EMMANUEL
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584613/
https://www.ncbi.nlm.nih.gov/pubmed/22134773
http://dx.doi.org/10.3892/ijo.2011.1271