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ANT2 suppression by shRNA restores miR-636 expression, thereby downregulating Ras and inhibiting tumorigenesis of hepatocellular carcinoma

MicroRNAs (miRNAs) participate in diverse biological functions and carcinogenesis by inhibiting specific gene expression. We previously reported that suppression of adenine nucleotide translocase 2 (ANT2) by using the short hairpin RNA (shRNA) approach has an antitumor effect in several cancer cells...

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Detalles Bibliográficos
Autores principales: Jang, Ji-Young, Lee, Young-Sin, Jeon, Yoon-Kyung, Lee, Kyoungbun, Jang, Ja-June, Kim, Chul-Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584659/
https://www.ncbi.nlm.nih.gov/pubmed/23306701
http://dx.doi.org/10.1038/emm.2013.1