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Analysis of Core Region from Egg White Lysozyme Forming Amyloid Fibrils

Some of the lysozyme mutants in humans cause systemic amyloidosis. Hen egg white lysozyme (HEWL) has been well studied as a model protein of amyloid fibrils formation. We previously identified an amyloid core region consisting of nine amino acids (designated as the K peptide), which is present at 54...

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Detalles Bibliográficos
Autores principales: Tokunaga, Yuhei, Sakakibara, Yukako, Kamada, Yoshiki, Watanabe, Kei-ichi, Sugimoto, Yasushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584918/
https://www.ncbi.nlm.nih.gov/pubmed/23459392
http://dx.doi.org/10.7150/ijbs.5380