Reflection on design and testing of pancreatic alpha-amylase inhibitors: an in silico comparison between rat and rabbit enzyme models

BACKGROUND: Inhibitors of pancreatic alpha-amylase are potential drugs to treat diabetes and obesity. In order to find compounds that would be effective amylase inhibitors, in vitro and in vivo models are usually used. The accuracy of models is limited, but these tools are nonetheless valuable. In v...

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Detalles Bibliográficos
Autores principales: Khalil-Moghaddam, Shiva, Ebrahim-Habibi, Azadeh, Pasalar, Parvin, Yaghmaei, Parichehreh, Hayati-Roodbari, Nasim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584935/
https://www.ncbi.nlm.nih.gov/pubmed/23352052
http://dx.doi.org/10.1186/2008-2231-20-77

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584935/
https://www.ncbi.nlm.nih.gov/pubmed/23352052
http://dx.doi.org/10.1186/2008-2231-20-77

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