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Three-component synthesis of pyrano[2,3-d]-pyrimidine dione derivatives facilitated by sulfonic acid nanoporous silica (SBA-Pr-SO(3)H) and their docking and urease inhibitory activity

BACKGROUND: A straightforward and efficient method for the synthesis of pyrano[2,3-d]pyrimidine diones derivatives from the reaction of barbituric acid, malononitrile and various aromatic aldehydes using SBA-Pr-SO(3)H as a nanocatalyst is reported. RESULTS: Reactions proceed with high efficiency und...

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Detalles Bibliográficos
Autores principales: Ziarani, Ghodsi Mohammadi, Faramarzi, Sakineh, Asadi, Shima, Badiei, Alireza, Bazl, Roya, Amanlou, Massoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584946/
https://www.ncbi.nlm.nih.gov/pubmed/23351402
http://dx.doi.org/10.1186/2008-2231-21-3