Cargando…
Three-component synthesis of pyrano[2,3-d]-pyrimidine dione derivatives facilitated by sulfonic acid nanoporous silica (SBA-Pr-SO(3)H) and their docking and urease inhibitory activity
BACKGROUND: A straightforward and efficient method for the synthesis of pyrano[2,3-d]pyrimidine diones derivatives from the reaction of barbituric acid, malononitrile and various aromatic aldehydes using SBA-Pr-SO(3)H as a nanocatalyst is reported. RESULTS: Reactions proceed with high efficiency und...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584946/ https://www.ncbi.nlm.nih.gov/pubmed/23351402 http://dx.doi.org/10.1186/2008-2231-21-3 |