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Neopterin Is a Cerebrospinal Fluid Marker for Treatment Outcome Evaluation in Patients Affected by Trypanosoma brucei gambiense Sleeping Sickness

BACKGROUND: Post-therapeutic follow-up is essential to confirm cure and to detect early treatment failures in patients affected by sleeping sickness (HAT). Current methods, based on finding of parasites in blood and cerebrospinal fluid (CSF) and counting of white blood cells (WBC) in CSF, are imperf...

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Detalles Bibliográficos
Autores principales: Tiberti, Natalia, Lejon, Veerle, Hainard, Alexandre, Courtioux, Bertrand, Robin, Xavier, Turck, Natacha, Kristensson, Krister, Matovu, Enock, Enyaru, John Charles, Mumba Ngoyi, Dieudonné, Krishna, Sanjeev, Bisser, Sylvie, Ndung′u, Joseph Mathu, Büscher, Philippe, Sanchez, Jean-Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585011/
https://www.ncbi.nlm.nih.gov/pubmed/23469311
http://dx.doi.org/10.1371/journal.pntd.0002088