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Age-Dependent Transition from Cell-Level to Population-Level Control in Murine Intestinal Homeostasis Revealed by Coalescence Analysis

In multi-cellular organisms, tissue homeostasis is maintained by an exquisite balance between stem cell proliferation and differentiation. This equilibrium can be achieved either at the single cell level (a.k.a. cell asymmetry), where stem cells follow strict asymmetric divisions, or the population...

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Detalles Bibliográficos
Autores principales: Hu, Zheng, Fu, Yun-Xin, Greenberg, Anthony J., Wu, Chung-I, Zhai, Weiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585040/
https://www.ncbi.nlm.nih.gov/pubmed/23468655
http://dx.doi.org/10.1371/journal.pgen.1003326