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RNAi–Based Functional Profiling of Loci from Blood Lipid Genome-Wide Association Studies Identifies Genes with Cholesterol-Regulatory Function

Genome-wide association studies (GWAS) are powerful tools to unravel genomic loci associated with common traits and complex human disease. However, GWAS only rarely reveal information on the exact genetic elements and pathogenic events underlying an association. In order to extract functional inform...

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Detalles Bibliográficos
Autores principales: Blattmann, Peter, Schuberth, Christian, Pepperkok, Rainer, Runz, Heiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585126/
https://www.ncbi.nlm.nih.gov/pubmed/23468663
http://dx.doi.org/10.1371/journal.pgen.1003338