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RNAi–Based Functional Profiling of Loci from Blood Lipid Genome-Wide Association Studies Identifies Genes with Cholesterol-Regulatory Function
Genome-wide association studies (GWAS) are powerful tools to unravel genomic loci associated with common traits and complex human disease. However, GWAS only rarely reveal information on the exact genetic elements and pathogenic events underlying an association. In order to extract functional inform...
Autores principales: | Blattmann, Peter, Schuberth, Christian, Pepperkok, Rainer, Runz, Heiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585126/ https://www.ncbi.nlm.nih.gov/pubmed/23468663 http://dx.doi.org/10.1371/journal.pgen.1003338 |
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