The Resistance of Human APOBEC3H to HIV-1 NL4-3 Molecular Clone Is Determined by a Single Amino Acid in Vif

Some human APOBEC3 cytidine deaminases have antiviral activity against HIV-1 and other retroviruses. The single deaminase domain APOBEC3H (A3H) enzyme is highly polymorphic and multiple A3H haplotypes have been identified. A3H haplotype II (A3H-hapII) possesses the strongest activity against HIV-1....

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Detalles Bibliográficos
Autores principales: Ooms, Marcel, Letko, Michael, Binka, Mawuena, Simon, Viviana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585137/
https://www.ncbi.nlm.nih.gov/pubmed/23469063
http://dx.doi.org/10.1371/journal.pone.0057744

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585137/
https://www.ncbi.nlm.nih.gov/pubmed/23469063
http://dx.doi.org/10.1371/journal.pone.0057744

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