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Systematic Functional Study of Cytochrome P450 2D6 Promoter Polymorphisms in the Chinese Han Population

The promoter polymorphisms of drug-metabolizing genes can lead to interindividual differences in gene expression, which may result in adverse drug effects and therapeutic failure. Based on the database of CYP2D6 gene polymorphisms in the Chinese Han population established by our group, we functional...

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Detalles Bibliográficos
Autores principales: Gong, Xueli, Liu, Yichen, Zhang, Xiaoqing, Wei, Zhiyun, Huo, Ran, Shen, Lu, He, Lin, Qin, Shengying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585152/
https://www.ncbi.nlm.nih.gov/pubmed/23469064
http://dx.doi.org/10.1371/journal.pone.0057764