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Systematic Functional Study of Cytochrome P450 2D6 Promoter Polymorphisms in the Chinese Han Population
The promoter polymorphisms of drug-metabolizing genes can lead to interindividual differences in gene expression, which may result in adverse drug effects and therapeutic failure. Based on the database of CYP2D6 gene polymorphisms in the Chinese Han population established by our group, we functional...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585152/ https://www.ncbi.nlm.nih.gov/pubmed/23469064 http://dx.doi.org/10.1371/journal.pone.0057764 |