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MCMV-mediated Inhibition of the Pro-apoptotic Bak Protein Is Required for Optimal In Vivo Replication

Successful replication and transmission of large DNA viruses such as the cytomegaloviruses (CMV) family of viruses depends on the ability to interfere with multiple aspects of the host immune response. Apoptosis functions as a host innate defence mechanism against viral infection, and the capacity t...

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Detalles Bibliográficos
Autores principales: Fleming, Peter, Kvansakul, Marc, Voigt, Valentina, Kile, Benjamin T., Kluck, Ruth M., Huang, David C. S., Degli-Esposti, Mariapia A., Andoniou, Christopher E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585157/
https://www.ncbi.nlm.nih.gov/pubmed/23468630
http://dx.doi.org/10.1371/journal.ppat.1003192