Cargando…
MCMV-mediated Inhibition of the Pro-apoptotic Bak Protein Is Required for Optimal In Vivo Replication
Successful replication and transmission of large DNA viruses such as the cytomegaloviruses (CMV) family of viruses depends on the ability to interfere with multiple aspects of the host immune response. Apoptosis functions as a host innate defence mechanism against viral infection, and the capacity t...
Autores principales: | Fleming, Peter, Kvansakul, Marc, Voigt, Valentina, Kile, Benjamin T., Kluck, Ruth M., Huang, David C. S., Degli-Esposti, Mariapia A., Andoniou, Christopher E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585157/ https://www.ncbi.nlm.nih.gov/pubmed/23468630 http://dx.doi.org/10.1371/journal.ppat.1003192 |
Ejemplares similares
-
A novel checkpoint in the Bcl-2–regulated apoptotic pathway revealed by murine cytomegalovirus infection of dendritic cells
por: Andoniou, Christopher E., et al.
Publicado: (2004) -
Ly49C-Dependent Control of MCMV Infection by NK Cells Is Cis-Regulated by MHC Class I Molecules
por: Forbes, Catherine A., et al.
Publicado: (2014) -
Bak apoptotic function is not directly regulated by phosphorylation
por: Tran, V H, et al.
Publicado: (2013) -
Cytomegalovirus establishes a latent reservoir and triggers long-lasting inflammation in the eye
por: Voigt, Valentina, et al.
Publicado: (2018) -
Translocation of a Bak C-Terminus Mutant from Cytosol to Mitochondria to Mediate Cytochrome c Release: Implications for Bak and Bax Apoptotic Function
por: Ferrer, Pedro Eitz, et al.
Publicado: (2012)