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Stimulation of Inositol 1,4,5-Trisphosphate (IP(3)) Receptor Subtypes by Adenophostin A and Its Analogues

Inositol 1,4,5-trisphosphate receptors (IP(3)R) are intracellular Ca(2+) channels. Most animal cells express mixtures of the three IP(3)R subtypes encoded by vertebrate genomes. Adenophostin A (AdA) is the most potent naturally occurring agonist of IP(3)R and it shares with IP(3) the essential featu...

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Detalles Bibliográficos
Autores principales: Saleem, Huma, Tovey, Stephen C., Riley, Andrew M., Potter, Barry V. L., Taylor, Colin W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585173/
https://www.ncbi.nlm.nih.gov/pubmed/23469136
http://dx.doi.org/10.1371/journal.pone.0058027