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Stimulation of Inositol 1,4,5-Trisphosphate (IP(3)) Receptor Subtypes by Adenophostin A and Its Analogues
Inositol 1,4,5-trisphosphate receptors (IP(3)R) are intracellular Ca(2+) channels. Most animal cells express mixtures of the three IP(3)R subtypes encoded by vertebrate genomes. Adenophostin A (AdA) is the most potent naturally occurring agonist of IP(3)R and it shares with IP(3) the essential featu...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585173/ https://www.ncbi.nlm.nih.gov/pubmed/23469136 http://dx.doi.org/10.1371/journal.pone.0058027 |