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Delivery of CdiA Nuclease Toxins into Target Cells during Contact-Dependent Growth Inhibition

Bacterial contact-dependent growth inhibition (CDI) is mediated by the CdiB/CdiA family of two-partner secretion proteins. CDI systems deploy a variety of distinct toxins, which are contained within the polymorphic C-terminal region (CdiA-CT) of CdiA proteins. Several CdiA-CTs are nucleases, suggest...

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Detalles Bibliográficos
Autores principales: Webb, Julia S., Nikolakakis, Kiel C., Willett, Julia L. E., Aoki, Stephanie K., Hayes, Christopher S., Low, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585180/
https://www.ncbi.nlm.nih.gov/pubmed/23469034
http://dx.doi.org/10.1371/journal.pone.0057609