Cargando…

COL-3, a Chemically Modified Tetracycline, Inhibits Lipopolysaccharide-Induced Microglia Activation and Cytokine Expression in the Brain

Microglia activation results in release of proinflammatory molecules including cytokines, which contribute to neuronal damage in the central nervous system (CNS) if not controlled. Tetracycline antibiotics such as minocycline inhibit microglial activation and cytokine expression during CNS inflammat...

Descripción completa

Detalles Bibliográficos
Autores principales: Edan, Rawan Abdulhameed, Luqmani, Yunus A., Masocha, Willias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585197/
https://www.ncbi.nlm.nih.gov/pubmed/23469077
http://dx.doi.org/10.1371/journal.pone.0057827