The N-Terminal Sequence of Prion Protein Consists an Epitope Specific to the Abnormal Isoform of Prion Protein (PrP(Sc))

The conformation of abnormal prion protein (PrP(Sc)) differs from that of cellular prion protein (PrP(C)), but the precise characteristics of PrP(Sc) remain to be elucidated. To clarify the properties of native PrP(Sc), we attempted to generate novel PrP(Sc)-specific monoclonal antibodies (mAbs) by...

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Detalles Bibliográficos
Autores principales: Masujin, Kentaro, Kaku-Ushiki, Yuko, Miwa, Ritsuko, Okada, Hiroyuki, Shimizu, Yoshihisa, Kasai, Kazuo, Matsuura, Yuichi, Yokoyama, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585212/
https://www.ncbi.nlm.nih.gov/pubmed/23469131
http://dx.doi.org/10.1371/journal.pone.0058013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585212/
https://www.ncbi.nlm.nih.gov/pubmed/23469131
http://dx.doi.org/10.1371/journal.pone.0058013

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