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In Type 1 Diabetes a Subset of Anti-Coxsackievirus B4 Antibodies Recognize Autoantigens and Induce Apoptosis of Pancreatic Beta Cells

Type 1 diabetes is characterized by autoimmune destruction of pancreatic beta cells. The role played by autoantibodies directed against beta cells antigens in the pathogenesis of the disease is still unclear. Coxsackievirus B infection has been linked to the onset of type 1 diabetes; however its pre...

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Detalles Bibliográficos
Autores principales: Bason, Caterina, Lorini, Renata, Lunardi, Claudio, Dolcino, Marzia, Giannattasio, Alessandro, d’Annunzio, Giuseppe, Rigo, Antonella, Pedemonte, Nicoletta, Corrocher, Roberto, Puccetti, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585221/
https://www.ncbi.nlm.nih.gov/pubmed/23469060
http://dx.doi.org/10.1371/journal.pone.0057729