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Decreased Dicer Expression Enhances SRP-Mediated Protein Targeting

We have shown that Dicer processes 7SL RNA into different fragments ranging from ∼20 to more than 200 nucleotides. Here we addressed the molecular functions of these 7SL RNA fragments and found that some of them functioned as dominant-negative regulators of the full-length 7SL RNA, interfering with...

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Detalles Bibliográficos
Autores principales: Ren, Yong-Feng, Li, Guiling, Xue, Yong-Feng, Zhang, Xue-Jiao, Song, Yi-Jiang, Lv, Lu, Wu, Jianmin, Fang, Yu-Xiao, Wang, Yu-Qun, Shi, Ke-Qing, Chen, Yong-ping, Tang, Kai-Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585229/
https://www.ncbi.nlm.nih.gov/pubmed/23468895
http://dx.doi.org/10.1371/journal.pone.0056950