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Towards Improved Quality of GPCR Models by Usage of Multiple Templates and Profile-Profile Comparison
G-protein coupled receptors (GPCRs) are targets of nearly one third of the drugs at the current pharmaceutical market. Despite their importance in many cellular processes the crystal structures are available for less than 20 unique GPCRs of the Rhodopsin-like class. Fortunately, even though involved...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585245/ https://www.ncbi.nlm.nih.gov/pubmed/23468878 http://dx.doi.org/10.1371/journal.pone.0056742 |