Altered Processing of Amyloid Precursor Protein in Cells Undergoing Apoptosis

Altered proteolysis of amyloid precursor protein is an important determinant of pathology development in Alzheimer's disease. Here, we describe the detection of two novel fragments of amyloid precursor protein in H4 neuroglioma cells undergoing apoptosis. Immunoreactivity of these 25–35 kDa fra...

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Detalles Bibliográficos
Autores principales: Fiorelli, Tina, Kirouac, Lisa, Padmanabhan, Jaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585261/
https://www.ncbi.nlm.nih.gov/pubmed/23469123
http://dx.doi.org/10.1371/journal.pone.0057979

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585261/
https://www.ncbi.nlm.nih.gov/pubmed/23469123
http://dx.doi.org/10.1371/journal.pone.0057979

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