Cyclin-Dependent Kinase 4 Phosphorylates and Positively Regulates PAX3-FOXO1 in Human Alveolar Rhabdomyosarcoma Cells

Alveolar rhabdomyosarcoma (ARMS) is an aggressive childhood muscle sarcoma with a 5-year survival rate of less than 30%. More than 80% of ARMSs harbor a PAX3-FOXO1 fusion transcription factor. However, expression of PAX3-FOXO1 in muscle cells alone is not sufficient and requires the loss of function...

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Detalles Bibliográficos
Autores principales: Liu, Lingling, Wu, Jing, Ong, Su Sien, Chen, Taosheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585270/
https://www.ncbi.nlm.nih.gov/pubmed/23469153
http://dx.doi.org/10.1371/journal.pone.0058193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585270/
https://www.ncbi.nlm.nih.gov/pubmed/23469153
http://dx.doi.org/10.1371/journal.pone.0058193

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