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Alpha-Fetoprotein Promoter-Driven Cre/LoxP-Switched RNA Interference for Hepatocellular Carcinoma Tissue-Specific Target Therapy

BACKGROUD: RNA interference (RNAi) has recently emerged as a potential treatment modality for hepatocellular carcinoma (HCC) therapy, but the lack of cellular targets and sustained efficacy limits its application. The purpose of this study is to develop an HCC tissue-specific RNAi system and investi...

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Detalles Bibliográficos
Autores principales: Peng, Yuan-Fei, Shi, Ying-Hong, Ding, Zhen-Bin, Zhou, Jian, Qiu, Shuang-Jian, Hui, Bo, Gu, Cheng-Yu, Yang, Hua, Liu, Wei-Ren, Fan, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585287/
https://www.ncbi.nlm.nih.gov/pubmed/23468839
http://dx.doi.org/10.1371/journal.pone.0053072