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CD57 Expression and Cytokine Production by T Cells in Lesional and Unaffected Skin from Patients with Psoriasis

BACKGROUND: The immunopathogenic mechanisms leading to psoriasis remain unresolved. CD57 is a marker of replicative inability and immunosenescence on CD8+ T cells and the proportion of CD57 expressing CD8+ T cells is increased in a number of inflammatory conditions. METHODOLOGY: We examined the expr...

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Detalles Bibliográficos
Autores principales: Batista, Mariana D., Tincati, Camilla, Milush, Jeffrey M., Ho, Emily L., Ndhlovu, Lishomwa C., York, Vanessa A., Kallas, Esper G., Kalil, Jorge, Keating, Sheila M., Norris, Philip J., Chang, David, Unemori, Patrick, Leslie, Kieron S., Maurer, Toby, Liao, Wilson, Nixon, Douglas F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585296/
https://www.ncbi.nlm.nih.gov/pubmed/23468834
http://dx.doi.org/10.1371/journal.pone.0052144