InterAKTions with FKBPs - Mutational and Pharmacological Exploration

The FK506-binding protein 51 (FKBP51) is an Hsp90-associated co-chaperone which regulates steroid receptors and kinases. In pancreatic cancer cell lines, FKBP51 was shown to recruit the phosphatase PHLPP to facilitate dephosphorylation of the kinase Akt, which was associated with reduced chemoresist...

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Detalles Bibliográficos
Autores principales: Fabian, Anne-Katrin, März, Andreas, Neimanis, Sonja, Biondi, Ricardo M., Kozany, Christian, Hausch, Felix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585324/
https://www.ncbi.nlm.nih.gov/pubmed/23469007
http://dx.doi.org/10.1371/journal.pone.0057508

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585324/
https://www.ncbi.nlm.nih.gov/pubmed/23469007
http://dx.doi.org/10.1371/journal.pone.0057508

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