Maternal Transmission of a Humanised Igf2r Allele Results in an Igf2 Dependent Hypomorphic and Non-Viable Growth Phenotype

The cation independent mannose 6-phosphate/insulin-like growth factor 2 receptor (IGF2R) functions in the transportation and regulation of insulin-like growth factor 2 (IGF2) and mannose 6-phosphate modified proteins. The relative and specific titration of IGF2 by high affinity binding of IGF2R repr...

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Detalles Bibliográficos
Autores principales: Hughes, Jennifer, Frago, Susana, Bühnemann, Claudia, Carter, Emma J., Hassan, A. Bassim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585325/
https://www.ncbi.nlm.nih.gov/pubmed/23468951
http://dx.doi.org/10.1371/journal.pone.0057270

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585325/
https://www.ncbi.nlm.nih.gov/pubmed/23468951
http://dx.doi.org/10.1371/journal.pone.0057270

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