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Isoflurane Preconditioning Confers Cardioprotection by Activation of ALDH2

The volatile anesthetic, isoflurane, protects the heart from ischemia/reperfusion (I/R) injury. Aldehyde dehydrogenase 2 (ALDH2) is thought to be an endogenous mechanism against ischemia-reperfusion injury possibly through detoxification of toxic aldehydes. We investigated whether cardioprotection b...

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Detalles Bibliográficos
Autores principales: Lang, Xiao-E, Wang, Xiong, Zhang, Ke-Rang, Lv, Ji-Yuan, Jin, Jian-Hua, Li, Qing-Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585331/
https://www.ncbi.nlm.nih.gov/pubmed/23468836
http://dx.doi.org/10.1371/journal.pone.0052469