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Znf202 Affects High Density Lipoprotein Cholesterol Levels and Promotes Hepatosteatosis in Hyperlipidemic Mice

BACKGROUND: The zinc finger protein Znf202 is a transcriptional suppressor of lipid related genes and has been linked to hypoalphalipoproteinemia. A functional role of Znf202 in lipid metabolism in vivo still remains to be established. METHODOLOGY AND PRINCIPAL FINDINGS: We generated mouse Znf202 ex...

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Detalles Bibliográficos
Autores principales: Vrins, Carlos L. J., Out, Ruud, van Santbrink, Peter, van der Zee, André, Mahmoudi, Tokameh, Groenendijk, Martine, Havekes, Louis M., van Berkel, Theo J. C., van Dijk, Ko Willems, Biessen, Erik A. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585336/
https://www.ncbi.nlm.nih.gov/pubmed/23469003
http://dx.doi.org/10.1371/journal.pone.0057492