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Clinical and Biological Relevance of Genomic Heterogeneity in Chronic Lymphocytic Leukemia

BACKGROUND: Chronic lymphocytic leukemia (CLL) is typically regarded as an indolent B-cell malignancy. However, there is wide variability with regards to need for therapy, time to progressive disease, and treatment response. This clinical variability is due, in part, to biological heterogeneity betw...

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Detalles Bibliográficos
Autores principales: Friedman, Daphne R., Lucas, Joseph E., Weinberg, J. Brice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585365/
https://www.ncbi.nlm.nih.gov/pubmed/23468975
http://dx.doi.org/10.1371/journal.pone.0057356