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Clinical and Biological Relevance of Genomic Heterogeneity in Chronic Lymphocytic Leukemia
BACKGROUND: Chronic lymphocytic leukemia (CLL) is typically regarded as an indolent B-cell malignancy. However, there is wide variability with regards to need for therapy, time to progressive disease, and treatment response. This clinical variability is due, in part, to biological heterogeneity betw...
Autores principales: | Friedman, Daphne R., Lucas, Joseph E., Weinberg, J. Brice |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585365/ https://www.ncbi.nlm.nih.gov/pubmed/23468975 http://dx.doi.org/10.1371/journal.pone.0057356 |
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